To investigate if the TSLP and CCL11/eotaxin-1 responses of asthmatic airways in vitro pertain to the in vivo state, we conducted a clinical study contrasting TSLP and CCL11/eotaxin-1 nasal airway protein levels in children with rhinovirus-induced asthma exacerbation, defined as hospitalization of a known asthmatic child due to active wheezing and (+) rhinovirus PCR testing (n = 20) vs. age-matched, non-asthmatic controls without wheezing or detectable respiratory virus by PCR (n = 20). The gene discussed is TSLP; the disease is asthma.