EZH2 and ovarian cancer: In light of the above model, we reasoned that in ovarian cancer patients with low EZH2 (i.e., low K4), increase of E2F6 mRNA (which results from an increase of transcription rate of E2F6, k5) may induce the expression of c-KIT mRNA (Rc), through miR-193a-mediated ceRNA mechanism.