TIP30, also called CC3 or HTATIP2, is a putative tumor suppressor initially identified by a differential display analysis of mRNA in highly metastatic human variant small cell lung carcinoma (v-SCLC), versus less metastatic classic small cell lung carcinoma (c-SCLC) cell lines [13]. The gene discussed is HTATIP2; the disease is small cell lung carcinoma.