This would be a significant boon, as LDN-193189 has already been used in rodent models of hepcidin-induced chronic anemia and fibrodysplasia ossificans progressiva (FOP) with constitutive activation of ACVR1, a type 1 BMP receptor kinase [49, 74]. Here, ACVR1 is linked to fibrodysplasia ossificans progressiva.