Thus, the absence of the consensus TAAT motifs in the ChIP targets together with MZF1 localization to the c-REL promoter (Fig. 4C) suggest that MIXL1-MZF1–containing multiprotein complexes, rather than MIXL1 homodimers, may be important in AML. The gene discussed is MZF1; the disease is acute myeloid leukemia.