Because higher Ror2 expression has a prior mentioned potential to serve as an independent biomarker in osteosarcoma, colorectal cancer, GIST,leiomyosarcoma, and as part of 34 gene panel in ccRCC we sought to determine whether Ror2 expression could serve as an independent prognostic factor in ccRCC [11], [16], [21], [26]. The gene discussed is ROR2; the disease is osteosarcoma.