The association is consistent with a pathway-based analysis in 2012, Dong J et al. examined 218 SNPs in 50 DNA repair genes in 568 lung cancer survivals and found 6 SNPs associated with lung cancer prognosis, including ATM rs189037, MRE11A rs11020802, ERCC2 rs1799793, MBD4 rs140693, XRCC1 rs25487, and PMS1 rs5742933 [8]. This evidence concerns the gene ERCC2 and lung cancer.