CD133 cell surface expression has been linked to stem cells, including endothelial progenitor cells, hematopoietic stem cells, fetal brain stem cells, embryonic epithelium, prostate epithelial stem cells, myogenic cells, and ependymal cells in the adult brain; as well as cancer stem cells in leukemia, teratocarcinoma, medulloblastoma, retinoblastoma and GBM, among other tumors [16], [17], [18], [19], [20], [21], [22], [23], [24]. Here, PROM1 is linked to glioblastoma.