ZFP36 and neoplasm: As predicted, a large fraction (80%, 40 out of 50 genes) of the mRNAs in the TTP-low tumor gene signature have AREs in their 3′UTRs, including UUAUUUAUU nonamers, UAUUUAUU octamers and AUUUA pentamers that have been shown to be bound by TTP in global analyses (Table 1) [8].