This study demonstrated for the first time that Antrodia camphorata exhibits potent antiplatelet activity via inhibiting both PKC and Akt activation in washed human platelets (Figure 4(b)). Antrodia camphorata has been used in traditional Chinese medicine to treat food poisoning, drug intoxication, diarrhea, abdominal pain, hypertension, skin irritation, and cancer [2]. Here, AKT1 is linked to Hypertension.