Interestingly, although the VMN contains GI neurons and plays a role in hypoglycemia detection, cfos activation was not detected in this brain region following insulin-induced hypoglycemia or glucoprivation (Niimi et al., 1995; Borg et al., 1997; Diggs-Andrews et al., 2010; Zhu et al., 2010; Szepietowska et al., 2011; Stanley et al., 2013). The gene discussed is INS; the disease is Hypoglycemia.