INS and Hypoglycemia: Moreover, the glucose sensitivity of both VMH GE and GI neurons shifts in parallel with the ability of the brain to sense and respond to insulin-induced hypoglycemia (Song and Routh, 2005, 2006; Kang et al., 2008; Diggs-Andrews et al., 2010; Fioramonti et al., 2010a,b, 2013).