The study further validated the well-established associations of HLA, PTPN22 and PTPN2 with JIA, in addition to confirming the involvement of other loci such as STAT4 with JIA, that were previously associated with the disease, but not at a genome-wide level of significance (p < 5 × 10-8)[6]. Here, PTPN2 is linked to juvenile idiopathic arthritis.