Comprehensive analysis of four sets of pathway networks (Figure 4A-D) revealed: (i) The pathway network (NF-network 2, LH-network 1, FSH-network 1, and LH/FSH-network 1) was highly similar among NF-, LH-, FSH-, and LH/FSH-NFPAs, and functions in cancer, cardiovascular system development and function, organism development, and nervous system development and function; and nodes ERK1/2, GH1, LH, insulin, and PRL play key roles in this common pathway network. This evidence concerns the gene INS and cancer.