PLOD1 and chronic obstructive pulmonary disease: (i) Ten biological toxicity events were common to four NFPA subtypes (NF-, LH-, FSH-, and LH/FSH-), including cardiac arrhythmia, liver hypertrophy, renal inflammation, renal nephritis, cardiac pulmonary embolism, cardiac stenosis, increased levels of bilirubin, kidney failure, increased levels of potassium, and glutathione depletion in liver.