We found that liver ENPP1 gene expression was −1.5 (95% CI −6.2 to 2.8) fold lower in the T2DM group when compared to the NGT group (Figure 1A, p = 0.04, ANOVA), while there was no difference in ENPP1 mRNA expression between the NGT and IGT group. Here, ENPP1 is linked to type 2 diabetes mellitus.