CTLA4 and autoimmune disease: An additional linkage of single-nucleotide polymorphisms (SNPs) in the region of CTLA-4 were subsequently found associated with a variety of autoimmune disorders that include type 1 diabetes, coeliac disease, myasthenia gravis, Hashimoto’s thyroiditis, systemic lupus erythematosus (SLE), and Wegener’s granulomatosis (8–12).