In addition, HN inhibits neurotoxicity by AD-relevant insults induced by other FAD genes including A617G-APP, L648P-APP, A246E-PS1, L286V-PS1, C410Y-PS1, and H163R-PS1 and other Aβ peptides (Aβ 1–42 and Aβ 25–35) (1). This evidence concerns the gene APP and Alzheimer disease.