Inhibition of the processing of Wnts derived from macrophages via IWP2-liposomes dampened the anagen-inducing effect of CL-lipo treatment, as documented by histological and immunofluorescence analysis of P-cad (enriched in the HG) (Figure 6F and 6G), and by the quantitative mRNA expression of HF-differentiation markers in total skin (Figure 6H). Here, CDH3 is linked to hydrops fetalis.