ACE and Hyperkalemia: The risk of developing hyperkalemia is increased by the use of drugs that disrupt K+ balance such as K+ sparing diuretics and blockers of the renin-angiotensin-aldosterone system (RAAS) (e.g., angiotensin-converting enzyme [ACE] inhibitors, angiotensin receptor blockers, spironolactone) [2], [4]–[6].