As shown in Table 2, OSA and short sleepduration were both individually associated with a significant increased risk for HTNafter adjustment for age, gender, obesity, diabetes, depression, current smoking,use of thyroid hormones, excessive daytime sleepiness, poor sleep complaint, timespent in slow wave sleep, overall arousal index, time in bed, and study site (model1). The gene discussed is TG; the disease is major depressive disorder.