TNF and hereditary angioedema: Recent observations of liver metastasis-like images in patients with digestive cancer, eventually leading to the discovery of HAE after months of misdiagnosis, have however dampened the notion of a usually easy differential diagnosis [10]; so have hemangioma-like and liver abscess-like images in patients with acquired immune suppression due to chemotherapy and/or anti-TNF biotherapeutic agents (Fig. 3) [50].