We analyzed a series of growth factors including epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), transforming growth factor beta (TGF-β) and fibroblast growth factor 2 (FGF2); growth factor receptors such as EGFR (EGF receptor), Flk1 (VEGF receptor 2); proteins related to tumor cell survival and apoptosis such as Bcl-2 and survivin; and some other proteins such as Nos3. Here, NOS3 is linked to neoplasm.