FOXA1 and breast cancer: In the basal-type cell lines, FOXA1 expression was much lower when compared with that of MCF-7, which supports the notion that FOXA1 is a marker for luminal subtype breast cancer.13 The expression of FOXA1 in MCF-7 cells was also significantly higher compared with the basal-type cell lines at the mRNA level (Figure 1b).