BRCA1 and neoplasm: Moreover, we also observed that FOXA1 expression was significantly lower in BRCA1-mutated tumours compared with BRCA2, BRCAx and BRCA2/x tumours (P<0.001, P=0.001 and P<0.001, respectively; Student's t-test; Figures 11f and g; Supplementary Figures S11 and S12).