PON1 and metabolic syndrome: In the ROC curve for PON-1, PON-1 prediction values < 180 U/L were associated with the diagnosis of metabolic syndrome with a sensitivity of 97.8%, a specificity of 95.5%, (area under the curve: 0.97; 95% confidence interval: 0.91–1.00; P < 0.001) (Figure 4).