The expression of Cx32 and Cx35 did not differ between the two subsets (data not shown), whereas Cx43 and Cx45 expression was significantly increased in the AML cells with monocytic differentiation (Fig. 2; p=0.0111 and p=0.0054, respectively, Mann-Whitney U test). The gene discussed is GJC1; the disease is acute myeloid leukemia.