CXCL8 and obesity due to melanocortin 4 receptor deficiency: IL-6 and IL-7 secretion by adipocytes was confirmed in 1997 and 2007, respectively, and plasmatic concentrations of both cytokines were positively correlated with obesity [43,44] Regarding IL-8, results are not conclusive: Okada and coworkers reported that IL-8 secretion was augmented after BM-MSC adipogenesis [45], similar to what we obtained, if we compare secretion of adipocyte-like cells derived from BM-MSC and basal secretion (47.8 ± 11.7 versus 628.3 ± 8.0 pg/106 cells/day; 24).