To further determine if BMI1 expression was replicated, we examined BMI1 mRNA expression in a panel of 8 patient-tumor derived pGBM xenograft models (Table 1), which were established through direct implantation of surgical specimens to the matched locations in mouse brains and strictly subtransplanted in vivo the brains of SCID mice [45,50]. This evidence concerns the gene BMI1 and neoplasm.