Likewise, rs9505298, rs7771314, rs2815128, rs13210097 and rs9392182 polymorphisms could be involved in cervical, esophageal and liver carcinomas, since they have been found in tumor tissues with a high TXNDC5 expression, a circumstance that could be linked to an increase in tumor growth and invasive potential [4]. The gene discussed is TXNDC5; the disease is hepatocellular carcinoma.