TXNDC5 is upregulated in several cancers such as hepatocellular [3], breast, cervical, colon, esophageal, liver, lung, stomach and uterine carcinomas [4,5], in colorectal cancer [6], in non-small cell lung carcinoma [7] and renal tumor tissue [8]. The gene discussed is TXNDC5; the disease is non-small cell lung carcinoma.