In addition, it has been reported that TP expression can be a predictive marker for oral 5-FU prodrug, which will be converted to 5-FU by TP.16,17 The treatment efficacy of doxifluridine was actually proven in gastric cancer, colon cancer, and other digestive tract cancers.10,11 These finding supports our therapeutic plan. The gene discussed is TYMP; the disease is gastric cancer.