AKR7A3 and neoplasm: Protein levels of AKR1C1, AKR7A3, and CBR1 significantly correlated with the respective transcript levels assessed by qPCR in the same tumor samples (Spearman ρ = 0.47, P = 0.003, Spearman ρ = 0.61, P < 0.001, and Spearman ρ = 0.44, P = 0.007, respectively) (Figure 4).