Surface proteins such as glycoprotein (involved in host cell attachment), F protein (directs viral penetration by membrane fusion and also mediates fusion of infected cells with their neighbours to form syncytia), matrix protein (important in virion morphogenesis), and small hydrophobic protein (involved in infection and replication) were targeted for the present study since these viruses are involved in fusion and replication and infection processes. This evidence concerns the gene ART4 and infection.