BRINP2 and Parkinson disease: Furthermore, inside the main hub cluster (Figure 4) three genes can be related to repair functions in PD: the growth arrest-specific gene 7, or GAS7, which promotes neurite outgrowth and motor neuron function [68, 69], FAM5B, alias BRIMP2, which codes for a BMP/RA-induced neural protein widely expressed in the central nervous system and related to neuron growth [57], and PARP4, which codes for a poly-ADP-ribose polymerase involved in the control of synaptic plasticity via major vault protein [64].