Patients taking oral anticoagulants and/or vitamin K deficiency should be excluded based on the clinical history and in Factor VII deficiency there is failure to improve the prothrombin time with vitamin K. It has been reported that many surgical procedures in patients with deficient Factor VII are well tolerated and may be performed without replacement therapy, such as caesarian section, tonsillectomy, and circumcision [10]. The gene discussed is F2; the disease is congenital factor VII deficiency.