BDNF and Alzheimer disease: For 3×Tg-AD mice, the MP supplementary diet significantly protected the hippocampal neurons (P < 0.01; Figure 5(a) and Table 3) and increased calcium binding protein level in the dentate gyrus (DG) of the hippocampus (P < 0.01; Figure 5(b) and Table 3) and an increased BDNF level in the hippocampus (P < 0.001; Figure 5(c) and Table 3).