Reduced Dicer and Drosha expression has been reported in various cancers, and based on previous publications on NSCLC[28, 29], there was an expectation that both Dicer and Drosha would have a positive prognostic impact on DSS, where reduced Dicer and Drosha expression would entail a poorer prognosis compared to higher expressions. The gene discussed is DICER1; the disease is non-small cell lung carcinoma.