HMGB1 and ocular melanoma: In comparison to β-glycerolphosphate stimulation alone, the addition of 50 ng/mL HMGB1 led to a further significant increase of silver nitrate enriched areas which, regarding the order of magnitude, leveled in the middle between the effect seen for OM alone and dexamethasone treated cultures, the latter showing the expected highest rate of mineralization after 21d (Figure 6(a)).