TXNDC12 and infection: Initially, we depleted granulocytes during S. TmWT infection using an α-Gr1 antibody (100 μg i.p., once per day; Materials and Methods; Fig. 6A) which binds to Ly6G on neutrophilic granulocytes (PMN) and to Ly6C, a marker expressed on neutrophils and on dendritic cells, some subpopulations of lymphocytes and some monocytes [44].