ATP2A2 and neoplasm: Comparably, a significantly elevated SERCA2 expression was detected in malignant tumor tissues (carcinoma, n=299) and lymph node metastasis (metastasis, n=8) (Figures 6a and c; one-way analysis of variance (ANOVA), P<0.0001), and such expression among 299 samples (stage I, n=171; stage II, n=83; stage III, n=45) was increased along with the clinical stages of carcinoma (Figures 6b and c; one-way ANOVA, P=0.0013).