By RNA-Seq of 12 T-ALL patient samples, we found that LYL1 and HHEX mRNA levels are highly correlated with LMO2 levels (r = 0.8, Fig. 6C), concurring with the view that LYL1 and HHEX are downstream targets of LMO2 in T-ALL. Here, LYL1 is linked to acute lymphoblastic leukemia.