In this study, we aim to widen the spectrum of phenotypes associated with PRRT2 mutations and investigate whether PRRT2 mutations are involved in febrile seizure-related epilepsy, including febrile seizures plus (FS+), generalized epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome (DS). Here, PRRT2 is linked to Febrile seizure (within the age range of 3 months to 6 years).