There are many coagulation related mediator genes in the schizophrenia-coagulation gene interaction network such as F2, F3, F5, F7, F8, F9, F10, F11, F13A1, F13B, FGA, FGB, FGG, FN1, GGCX, PLAT, PROS1, SERPINA5, SERPINB6, SERPINB8 and SERPINF2. This evidence concerns the gene SERPINB8 and schizophrenia.