Additionally, Joshi et al. [56], using a pathway-based analysis, have noted over-representation of ESR1, GATA3, MYC, XBP1, FOXA1 and MSX2 in luminal tumours, and NFκB1, C/EBPβ, FOXO3, JUN, POU2F3 and FOXO1 in basal-like tumours. This evidence concerns the gene MSX2 and neoplasm.