The complex DDX20-GEMIN4-PPP4C-PPP4R2 associated with the SMN (survival of motor neuron), and SNAP23-STX4-VAMP3-VAMP8 associated with vesicular transport, docking and/or fusion of synaptic vesicles with the presynaptic membrane (http://www.genecards.org) [14], support tumorigenic invasion of neural cells in pancreatic cancer [35]. This evidence concerns the gene STX4 and familial pancreatic carcinoma.