IFNG and infection: ECM-susceptible mice, co-infected with PbA and PbK173 are completely protected from ECM and this protection was found to be associated with increased IFN-γ in the blood at 24 h post-infection and an increase in transcriptional abundance of IFN-γ, IL-10 and IL-12 in both the liver and spleen (Mitchell et al., 2005).