An increase in traditional circulating inflammatory markers like C-reactive protein (CRP), IL-6, IL-8, TNF-α, and endothelin-1, as well as novel markers like the urokinase plasminogen activator receptor (SuPAR), have repeatedly been detected in several studies on T1DM and T2DM (55–61). This evidence concerns the gene CRP and type 2 diabetes mellitus.