In addition to the above three cytokines, many other cytokine/chemokines are considered to be correlated with dengue disease severity, including IL-1 β, IL-2, IL-6, IL-8, IL-10, IL-13, IL-18, IFN-γ, TNF-α, and MCP1 [42,44-50]. The gene discussed is IL6; the disease is dengue disease.