PLAUR and cancer: On the contrary, in the analysis of DSS we found an association between high uPAR antigen levels and an increased risk of cancer-related death with a trend towards significance for patients with organ-confined tumours in either univariate or multivariate Cox regression analysis with HRs of 3.15 (95% CI 0.97-10.2, P = 0.057) and 3.09 (95% CI 0.88-10.8, P = 0.077), respectively (Additional file1: Tables S2 and S3).