Patients with pT1+2 tumours with high levels of uPA and/or uPAR showed a significantly increased risk of cancer-related death (HR = 9.83; 95% CI 1.21-79.6, P = 0.032) compared to pT1+2 patients who had low uPA and uPAR levels (Table 5). The gene discussed is PLAU; the disease is neoplasm.