Anthropometrical characteristics and baseline examination and laboratory values, oral glucose tolerance test (OGTT) results and areas under the curve (AUCs), estimates of insulin sensitivity and insulin secretion parameters and indexes in non-diabetic insulin-resistant (IR) and –sensitive (IS) subjects without acromegaly (NonACRO), without acromegaly and with similar body mass index ((NonACRO-sBMI), and acromegaly (ACRO). The gene discussed is INS; the disease is acromegaly.