FPR2 and Anxiety: Although we found no statistically significant difference between Fpr2/3-/- mice and wild-type control mice with respect to ambulation and rearing (Fig. 1, left and middle panels, respectively), Fpr2/3-/- mice showed reduced thigmotaxis (walking along the edges) and significantly increased centre crossings (Fig. 1, right panel) indicating a reduced level of anxiety [56], [57].