Cultured major pelvic nerve ganglion is an important and almost indispensable tool for the study of physiology and pathophysiology of neuropathy, Lin et al. [25,26] reported that BDNF and VEGF promote neurite growth from cultured MPG; BDNF promotes MPG neurite growth primarily by activating the JAK/STAT pathway. Here, BDNF is linked to neuropathy.