Interestingly, nitazoxanide was also found to be highly active against cancer cells such as the colon carcinoma cell line Caco2, and this effect was shown to be based on the interaction of the compound with glutathione-S-transferase Pi (GSTP1), which is highly expressed in colon cancer cells (Müller et al., 2008). The gene discussed is GSTP1; the disease is colon carcinoma.