Nevertheless, the fact that KRAS transfected cells, but not the parental cells, were highly susceptible to oncrasin-1 and NSC-743380 [19, 22] indicates that KRAS may upregulate SULT1A1 in some cancer cells, and that SULT1A1 overexpression may occur in a subset of cancers with activation of RAS signaling pathways. The gene discussed is KRAS; the disease is cancer.