Previously it was reported that treatment of mouse primary hepatocytes with peroxisomes proliferators (including Wy14643) for 24 hours led to upregulation of 11 genes related to liver cancer (i.e. Angptl4, Bnip3, Dbi, Fabp1, Fabp2, Fasn, HifIa, Lgals3, Ly6d, Mgll, SerpineI) [54]. This evidence concerns the gene LGALS3 and liver cancer.